Unlocking the Grandline Vanguards Devil Fruit system is a major step forward in powering up your team. Once players reach level 120, the Devil Fruit system becomes available, introducing a new layer of strategy through active and passive combat effects. With proper farming and planning, these fruits can shift the tide of battle and define your team’s success in both PvE and PvP.
This guide explains how the Devil Fruit system works, which fruits are considered top-tier, and the most effective ways to collect Devil Fruit Samples to build your ideal setup.
What is the Devil Fruit System in Grandline Vanguards?
The Devil Fruit system in Grandline Vanguards unlocks at level 120, offering players the ability to equip up to four Devil Fruit slots. These fruits function similarly to supportive artifacts or passive units. Each fruit can provide either active or passive effects during battle, such as healing, crowd control, or direct damage.
Players must unlock and upgrade these slots using Devil Fruit Samples, which serve as the core material for creating fruits. Because each fruit has different effects, choosing and combining the right ones is essential to enhancing your team’s performance.
How to Get Devil Fruit Samples
Devil Fruit Samples are the key resource needed to produce Devil Fruits. There are several ways to collect them:
Devil Fruit Salvage – A dedicated feature for breaking down materials into samples.
Advance Customization – Higher-tier crafting and enhancement system.
Uncharted Seas – A core game mode that provides Samples as stage rewards.
Egg Head Area – Special region offering valuable Samples through combat rewards.
Uncharted Sea Shop – Exchange shop where Samples can be purchased using in-game currency.
Stage Rewards and Leaderboards – High-ranking players gain access to better Samples.
Once collected, Samples are used in an incubation system to craft Devil Fruits. This process takes time and yields random results depending on sample quality and type. Golden Samples, in particular, offer a higher chance of producing top-tier fruits.
Best Devil Fruits in Grandline Vanguards – S-Tier List
Not all Devil Fruits are created equal. Based on combat utility and synergy, these are the best S-tier Devil Fruits currently available:
Azur Dragon Form
Boosts team speed and deals physical damage to all enemies—great for fast-paced teams.Rumble Rumble Fruit
Deals physical damage while benefiting from enemy debuffs; can also stun buff-heavy enemies.Tremor Fruit
Magic attack targeting 1 to 5 enemies with a chance to stun, excellent for control builds.Phoenix Fruit
Heals based on Max HP and applies a shield to allies with low health, ideal for sustain teams.Ice Ice Fruit
High single-target physical damage and speed-stealing effect make it a top choice for burst teams.Singsing Fruit
Removes all debuffs and delivers a massive heal to the user—best for support roles.Law Fruit
Blocks enemy buffs and deals physical damage, ideal for PvP disruption.
Mid-Tier Devil Fruits – A and B Tier
These Devil Fruits are still useful depending on your composition but are generally situational:
Flowerflower Fruit
Provides lifesteal and healing to the lowest HP ally—solid support in longer battles.Chopchop Fruit
Physical damage dealer with a chance to apply armor break.Bubble Bubble Fruit
A basic healer fruit with average recovery power.Magnet Magnet Fruit
Temporarily boosts critical rate for your primary attacker—works best with high-DPS teams.
While not as powerful as S-tier fruits, these options are still viable for players in mid-game progression or in need of specific utility.
Tips for Farming Devil Fruits Efficiently
If you want consistent access to powerful Devil Fruits, you’ll need a good strategy for farming Samples:
Focus on Uncharted Seas and Egg Head zones to gather higher-quality Samples more frequently.
Use Golden Samples in incubation for better chances at crafting S-tier fruits.
Advance through leaderboard tiers to unlock superior reward pools tied to Sample quality.
Maximize your time by running multiple incubation processes so you always have a fruit in production.
Don’t hoard low-quality Samples—use them for Salvage to clear inventory and upgrade others.
Players who invest time in gathering and crafting Devil Fruits gain an undeniable advantage in both solo and competitive play, especially when effects like stuns, healing, and buff disruption are involved.
Final Thoughts
The Devil Fruit system in Grandline Vanguards adds rich customization to team building, offering strategic tools through both offensive and supportive effects. By understanding which fruits rank highest in the current meta and farming the right materials through Uncharted Seas, Egg Head, and Sample Salvage, players can develop powerful combinations tailored to their playstyle.
Whether you’re seeking speed buffs, healing, stuns, or control, the right Devil Fruits will give you the edge in every battle. Start collecting today, and make the most out of every slot in your lineup.